Yes, you can specify that a space is regularly occupied, e.g. if you have a team meeting every Tuesday from 09am to 11am. To do this, click on the first day of the series, mark the time (hold mouse), specify the reason why the space is occupied, and click "Add Series Unavailability".
IMPORTANT: On the next page, you must specify when the series ends (date or number of events), otherwise the series will not be saved. The corresponding time window is displayed in red and provided with the reason (latter is not published). If a guest searches a space for one of these times (partial or whole), the space is not displayed in the search results.